Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Q
PROVIDER: S-EPMC5752502 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Zhang Qiao Q Yang Zhe Z Han Qiaoqiao Q Bai Honggang H Wang Yanling Y Yi Xiaojia X Yi Zihan Z Yang Lijuan L Jiang Lu L Song Xin X Kuang Yingmin Y Zhu Yuechun Y
Oncotarget 20171120 65
Ectopic Glucose 6-phosphate dehydrogenase (G6PD) expression plays important role in tumor cell metabolic reprogramming and results in poor prognosis of multiple malignancies. Our previous study indicated that G6PD is overexpressed in clear cell renal cell carcinoma (ccRCC), the most common subtype of RCC. However, its role in RCC is still unclear. Here, we demonstrate that G6PD is not only up-regulated in all types of RCC specimens but also displays higher activities in RCC cell lines. G6PD over ...[more]