Ontology highlight
ABSTRACT:
SUBMITTER: Clarisse D
PROVIDER: S-EPMC5752551 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Clarisse Dorien D Thommis Jonathan J Van Wesemael Karlien K Houtman René R Ratman Dariusz D Tavernier Jan J Offner Fritz F Beck Ilse I De Bosscher Karolien K
Oncotarget 20171130 65
Coregulators cooperate with nuclear receptors, such as the glucocorticoid receptor (GR), to enhance or repress transcription. These regulatory proteins are implicated in cancer, yet, their role in lymphoid malignancies, including multiple myeloma (MM) and acute lymphoblastic leukemia (ALL), is largely unknown. Here, we report the use and extension of the microarray assay for real-time nuclear receptor coregulator interactions (MARCoNI) technology to detect coregulator associations with endogenou ...[more]