Ontology highlight
ABSTRACT:
SUBMITTER: Wang R
PROVIDER: S-EPMC5753232 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Wang Ruijia R Nambiar Ram R Zheng Dinghai D Tian Bin B
Nucleic acids research 20180101 D1
PolyA_DB is a database cataloging cleavage and polyadenylation sites (PASs) in several genomes. Previous versions were based mainly on expressed sequence tags (ESTs), which had a limited amount and could lead to inaccurate PAS identification due to the presence of internal A-rich sequences in transcripts. Here, we present an updated version of the database based solely on deep sequencing data. First, PASs are mapped by the 3' region extraction and deep sequencing (3'READS) method, ensuring unequ ...[more]