HEDD: Human Enhancer Disease Database.
Ontology highlight
ABSTRACT:
SUBMITTER: Wang Z
PROVIDER: S-EPMC5753236 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Publications
HEDD: Human Enhancer Disease Database.
Wang Zhen Z Zhang Quanwei Q Zhang Wen W Lin Jhih-Rong JR Cai Ying Y Mitra Joydeep J Zhang Zhengdong D ZD
Nucleic acids research 20180101 D1
Enhancers, as specialized genomic cis-regulatory elements, activate transcription of their target genes and play an important role in pathogenesis of many human complex diseases. Despite recent systematic identification of them in the human genome, currently there is an urgent need for comprehensive annotation databases of human enhancers with a focus on their disease connections. In response, we built the Human Enhancer Disease Database (HEDD) to facilitate studies of enhancers and their potent ...[more]
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