Ontology highlight
ABSTRACT:
SUBMITTER: Smirnov P
PROVIDER: S-EPMC5753377 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Smirnov Petr P Kofia Victor V Maru Alexander A Freeman Mark M Ho Chantal C El-Hachem Nehme N Adam George-Alexandru GA Ba-Alawi Wail W Safikhani Zhaleh Z Haibe-Kains Benjamin B
Nucleic acids research 20180101 D1
Recent cancer pharmacogenomic studies profiled large panels of cell lines against hundreds of approved drugs and experimental chemical compounds. The overarching goal of these screens is to measure sensitivity of cell lines to chemical perturbations, correlate these measures to genomic features, and thereby develop novel predictors of drug response. However, leveraging these valuable data is challenging due to the lack of standards for annotating cell lines and chemical compounds, and quantifyin ...[more]