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The diagnostic value of glycated albumin in gestational diabetes mellitus.


ABSTRACT:

Purpose

Our objective was to compare the diagnostic performance of glycated hemoglobin (HbA1c), GA, and fasting plasma glucose (FPG) for the diagnosis of GDM.

Methods

Women at their late second or early third trimesters seen from October 2011 to April 2012 were studied. GDM was diagnosed based on oral glucose tolerance test results, and GA and HbA1c were measured at the same time. Patients were divided into two groups (with and without GDM), and areas under the receiver-operating characteristic curves (AUCs) were calculated to determine the diagnostic value of FPG, GA, and HbA1c.

Results

A total of 698 women were included, of which 232 (33.2%) had GDM. Overall, FPG had the highest AUC for the detection of GDM, and was significantly higher than that of GA (0.692 vs. 0.568, p?ConclusionsThese results do not support the use of GA as a screening tool for GDM.

SUBMITTER: Zhu J 

PROVIDER: S-EPMC5754373 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature

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Publications

The diagnostic value of glycated albumin in gestational diabetes mellitus.

Zhu Jieping J   Chen Yu Y   Li Changbin C   Tao Minfang M   Teng Yincheng Y  

Journal of endocrinological investigation 20170606 1


<h4>Purpose</h4>Our objective was to compare the diagnostic performance of glycated hemoglobin (HbA1c), GA, and fasting plasma glucose (FPG) for the diagnosis of GDM.<h4>Methods</h4>Women at their late second or early third trimesters seen from October 2011 to April 2012 were studied. GDM was diagnosed based on oral glucose tolerance test results, and GA and HbA1c were measured at the same time. Patients were divided into two groups (with and without GDM), and areas under the receiver-operating  ...[more]

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