Ontology highlight
ABSTRACT:
SUBMITTER: Gonzales J
PROVIDER: S-EPMC5754869 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Gonzales John J Doan Thuy T Shantha Jessica G JG Bloomer Michele M Wilson Michael R MR DeRisi Joseph L JL Acharya Nisha N
The British journal of ophthalmology 20171109 1
<h4>Introduction</h4>Currently, the detection of pathogens or mutations associated with intraocular lymphomas heavily relies on prespecified, directed PCRs. With metagenomic deep sequencing (MDS), an unbiased high-throughput sequencing approach, all pathogens as well as all mutations present in the host's genome can be detected in the same small amount of ocular fluid.<h4>Methods</h4>In this cross-sectional case series, aqueous fluid samples from two patients were submitted to MDS to identify pa ...[more]