Ontology highlight
ABSTRACT:
SUBMITTER: Schechter ME
PROVIDER: S-EPMC5755598 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Schechter Melissa E ME Andrade Bruno B BB He Tianyu T Richter George Haret GH Tosh Kevin W KW Policicchio Benjamin B BB Singh Amrit A Raehtz Kevin D KD Sheikh Virginia V Ma Dongying D Brocca-Cofano Egidio E Apetrei Cristian C Tracy Russel R Ribeiro Ruy M RM Sher Alan A Francischetti Ivo M B IMB Pandrea Ivona I Sereti Irini I
Science translational medicine 20170801 405
In HIV infection, persistent inflammation despite effective antiretroviral therapy is linked to increased risk of noninfectious chronic complications such as cardiovascular and thromboembolic disease. A better understanding of inflammatory and coagulation pathways in HIV infection is needed to optimize clinical care. Markers of monocyte activation and coagulation independently predict morbidity and mortality associated with non-AIDS events. We identified a specific subset of monocytes that expre ...[more]