Ontology highlight
ABSTRACT:
SUBMITTER: Puccini A
PROVIDER: S-EPMC5757873 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Puccini Alberto A Berger Martin D MD Naseem Madiha M Tokunaga Ryuma R Battaglin Francesca F Cao Shu S Hanna Diana L DL McSkane Michelle M Soni Shivani S Zhang Wu W Lenz Heinz-Josef HJ
Biochimica et biophysica acta. Reviews on cancer 20170920 2
Colorectal cancer (CRC) is a heterogeneous disease with distinct molecular and clinical features, which reflects the wide range of prognostic outcomes and treatment responses observed among CRC patients worldwide. Our understanding of the CRC epigenome has been largely developed over the last decade and it is now believed that among thousands of epigenetic alterations present in each tumor, a small subgroup of these may be considered as a CRC driver event. DNA methylation profiles have been the ...[more]