Ontology highlight
ABSTRACT:
SUBMITTER: Boley DA
PROVIDER: S-EPMC5759956 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Boley Danielle A DA Zhang Zhenbin Z Dovichi Norman J NJ
Journal of chromatography. A 20170708
While capillary zone electrophoresis (CZE) provides dramatically improved numbers of peptide identifications compared with reversed-phase chromatography for bottom-up proteomics of mass limited samples, CZE inevitably produces lower numbers of peptide identifications than RPLC for larger samples. One reason for this poorer performance is the dead time between injection of samples and subsequent appearance of the fastest moving component. This dead time is typically 25% of the separation window i ...[more]