Ontology highlight
ABSTRACT:
SUBMITTER: Zhang JA
PROVIDER: S-EPMC5760171 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Zhang Jun-Ai JA Liu Gan-Bin GB Zheng Bi-Ying BY Lu Yuan-Bin YB Gao Yu-Chi YC Cai Xiao-Zhen XZ Dai You-Chao YC Yu Shi-Yan SY Jia Yan Y Chen Chen C Zhuang Ze-Gang ZG Wang Xin X Wang Wan-Dang WD Fu Xiao-Xia XX Yi Lai-Long LL Shen Ling L Chen Zheng W ZW Xu Jun-Fa JF
Molecular immunology 20160929
Roles of human IL-37 in infections remain poorly characterized. Although plasma IL-37 is elevated in patients with tuberculosis (TB), IL-37 source and immune correlate in TB have not been investigated. It is also unknown whether and how TB can influence the ability of immune cells to mount innate responses of IL-37 and pre-inflammatory cytokines. Here, we demonstrated that IL-37b-producing monocytes coincided with a source of elevated plasma IL-37b in TB patients. While IL-37b production in TB w ...[more]