The self-reference effect in dementia: Differential involvement of cortical midline structures in Alzheimer's disease and behavioural-variant frontotemporal dementia.
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ABSTRACT:
SUBMITTER: Wong S
PROVIDER: S-EPMC5760181 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
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The self-reference effect in dementia: Differential involvement of cortical midline structures in Alzheimer's disease and behavioural-variant frontotemporal dementia.
Wong Stephanie S Irish Muireann M Leshikar Eric D ED Duarte Audrey A Bertoux Maxime M Savage Greg G Hodges John R JR Piguet Olivier O Hornberger Michael M
Cortex; a journal devoted to the study of the nervous system and behavior 20161003
Encoding information in reference to the self enhances subsequent memory for the source of this information. In healthy adults, self-referential processing has been proposed to be mediated by the cortical midline structures (CMS), with functional differentiation between anterior-ventral, anterior-dorsal and posterior regions. While both Alzheimer's disease (AD) and behavioural-variant frontotemporal dementia (bvFTD) patients show source memory impairment, it remains unclear whether they show a t ...[more]
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