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ABSTRACT:
SUBMITTER: Deconinck E
PROVIDER: S-EPMC5761215 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Deconinck E E Andriessens S S Bothy J L JL Courselle P P De Beer J O JO
Journal of pharmaceutical analysis 20140313 4
Counterfeit medicines are a growing problem in both developing and industrialised countries. In general the evaluation of these medicines is limited to the identification and the dosage of the active ingredients. In this study in vitro dissolution tests were conducted on two sets of counterfeit medicines containing PDE-5 inhibitors (sildenafil citrate and tadalafil). The dissolution profiles were statistically compared to the ones of the genuine products using the <i>f</i><sub>2</sub>-method and ...[more]