Ontology highlight
ABSTRACT:
SUBMITTER: Levade I
PROVIDER: S-EPMC5761273 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Levade Inès I Terrat Yves Y Leducq Jean-Baptiste JB Weil Ana A AA Mayo-Smith Leslie M LM Chowdhury Fahima F Khan Ashraful I AI Boncy Jacques J Buteau Josiane J Ivers Louise C LC Ryan Edward T ET Charles Richelle C RC Calderwood Stephen B SB Qadri Firdausi F Harris Jason B JB LaRocque Regina C RC Shapiro B Jesse BJ
Microbial genomics 20171201 12
Cholera is a severe, water-borne diarrhoeal disease caused by toxin-producing strains of the bacterium Vibrio cholerae. Comparative genomics has revealed 'waves' of cholera transmission and evolution, in which clones are successively replaced over decades and centuries. However, the extent of V. cholerae genetic diversity within an epidemic or even within an individual patient is poorly understood. Here, we characterized V. cholerae genomic diversity at a micro-epidemiological level within and b ...[more]