Ontology highlight
ABSTRACT:
SUBMITTER: Abiramasundari A
PROVIDER: S-EPMC5761480 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Abiramasundari A A Joshi Rahul P RP Jalani Hitesh B HB Sharma Jayesh A JA Pandya Dhaivat H DH Pandya Amit N AN Sudarsanam Vasudevan V Vasu Kamala K KK
Journal of pharmaceutical analysis 20140125 6
The stability of the drug actarit was studied under different stress conditions like hydrolysis (acid, alkaline and neutral), oxidation, photolysis and thermal degradation as recommended by International Conference on Harmonization (ICH) guidelines. Drug was found to be unstable in acidic, basic and photolytic conditions and produced a common degradation product while oxidative stress condition produced three additional degradation products. Drug was impassive to neutral hydrolysis, dry thermal ...[more]