Ontology highlight
ABSTRACT:
SUBMITTER: Zhao F
PROVIDER: S-EPMC5762283 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Zhao Feng F Tian Wei W Zeng Ming M Xia Jianling J Hu Honglin H Hao Xinbao X Han Liangfu L Liu Hao H He Yangke Y Zhu Xueqiang X Liang Liang L Ao Rui R Wei Min M Deng Lili L Wei Yuquan Y
Oncotarget 20171128 67
<h4>Background</h4>To study safety and efficacy of apatinib in combination of radiotherapy in patients with symptomatic bony disease prostate cancer(SBPC), based on the potential synergistic antitumor activity between apatinib and Radiation Therapy (RT).<h4>Patients and methods</h4>In phase I dose escalation part, 18 patients received apatinib dose at 250 mg every other day, 250 mg daily and 500 mg daily. In phase II part, the 250 mg daily cohorts were expanded to 20 patients in combination of R ...[more]