Identification of novel diagnostic biomarkers for thyroid carcinoma.
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ABSTRACT:
SUBMITTER: Wang X
PROVIDER: S-EPMC5762342 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Publications
Identification of novel diagnostic biomarkers for thyroid carcinoma.
Wang Xiliang X Zhang Qing Q Cai Zhiming Z Dai Yifan Y Mou Lisha L
Oncotarget 20171204 67
Thyroid carcinoma (THCA) is the most universal endocrine malignancy worldwide. Unfortunately, a limited number of large-scale analyses have been performed to identify biomarkers for THCA. Here, we conducted a meta-analysis using 505 THCA patients and 59 normal controls from The Cancer Genome Atlas. After identifying differentially expressed long non-coding RNA (lncRNA) and protein coding genes (PCG), we found vast difference in various lncRNA-PCG co-expressed pairs in THCA. A dysregulation netwo ...[more]
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