Ontology highlight
ABSTRACT:
SUBMITTER: Chen G
PROVIDER: S-EPMC5764386 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Chen Guanglin G Du Chunxia C Shen Ziyang Z Peng Lei L Xie Hua H Zang Rujin R Li Hongxing H Xia Yankai Y Tang Weibing W
Aging 20171201 12
<b>Background</b>Hirschsprung's disease (HSCR) is a common digestive disease caused by impaired development of neural crest cells. Some studies have revealed the roles of microRNA (miRNA) in various diseases. But the function of miRNA in HSCR needs further investigation.<b>Methods</b>We adopted qRT-PCR and immunoblot analyses to explore the relative expression of miR-939 and LRSAM1 in 80 HSCR bowel tissues and 80 normal bowel tissues. CCK-8 assay, transwell assay and flow cytometry were used to ...[more]