Ontology highlight
ABSTRACT:
SUBMITTER: Lentini G
PROVIDER: S-EPMC5764780 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Lentini Gaelle G Dos Santos Pacheco Nicolas N Burleigh Barbara A BA
Cellular microbiology 20171128 2
Trypanosoma cruzi is the kinetoplastid protozoan parasite that causes human Chagas disease, a chronic disease with complex outcomes including severe cardiomyopathy and sudden death. In mammalian hosts, T. cruzi colonises a wide range of tissues and cell types where it replicates within the host cell cytoplasm. Like all intracellular pathogens, T. cruzi amastigotes must interact with its immediate host cell environment in a manner that facilitates access to nutrients and promotes a suitable niche ...[more]