Novel mobility test to assess functional vision in patients with inherited retinal dystrophies.

ABSTRACT:

Importance

This novel endpoint tracks functional vision changes in patients with inherited retinal dystrophies (IRDs) over time.

Background

The aims of the study were to determine whether a multi-luminance mobility test (MLMT) can detect functional vision changes over time in subjects with IRDs and to assess natural history and potential effects of investigational agents.

Design

This is a prospective, observational study.

Participants

Sixty-two subjects were enrolled. Sixty (29 normal sighted and 31 visually impaired) were eligible; 54 (28 visually impaired and 26 normal-sighted) completed all testing visits.

Methods

Subjects navigated MLMT courses three times over 1 year. At each visit, subjects completed testing using individual eyes, and both eyes, at

SUBMITTER: Chung DC 

PROVIDER: S-EPMC5764825 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature