HLA-DR expression in neonates after cardiac surgery under cardiopulmonary bypass: a pilot study.
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ABSTRACT:
SUBMITTER: Chenouard A
PROVIDER: S-EPMC5764905 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Publications
HLA-DR expression in neonates after cardiac surgery under cardiopulmonary bypass: a pilot study.
Chenouard Alexis A Braudeau Cécile C Cottron Nicolas N Bourgoin Pierre P Salabert Nina N Roquilly Antoine A Josien Régis R Joram Nicolas N Asehnoune Karim K
Intensive care medicine experimental 20180111 1
Monocyte HLA-DR expression has been reported as a marker of immunosuppression and a predictor of sepsis development. However, to date, there is no report on monocyte HLA-DR monitoring exclusively in neonates (< 28 days of life) who underwent cardiac surgery under cardiopulmonary bypass (CPB), which have a high risk of nosocomial infection. In this pilot study, we studied nine neonates with a diagnosis of congenital heart disease requiring surgery under CPB. There was a significant reduction in m ...[more]
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Project description: Not available
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