Ontology highlight
ABSTRACT:
SUBMITTER: Diestelhorst J
PROVIDER: S-EPMC5764983 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Diestelhorst Jana J Junge Norman N Jonigk Danny D Schlue Jerome J Falk Christine S CS Manns Michael P MP Baumann Ulrich U Jaeckel Elmar E Taubert Richard R
Scientific reports 20180111 1
Although autoimmune hepatitis (AIH) can be treated with corticosteroid-based first-line therapy, incomplete remission is associated with progressive liver fibrosis. So far accepted predictors of the subsequent treatment response of AIH patients are lacking. Therefore, we analysed baseline parameters, including iron homeostasis and cytokine levels, in 60 children with paediatric AIH (pAIH). In contrast to adults, elevated serum markers indicating iron overload were not commonly found in children. ...[more]