Ontology highlight
ABSTRACT:
SUBMITTER: Meerstein-Kessel L
PROVIDER: S-EPMC5765010 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Meerstein-Kessel Lisette L van der Lee Robin R Stone Will W Lanke Kjerstin K Baker David A DA Alano Pietro P Silvestrini Francesco F Janse Chris J CJ Khan Shahid M SM van de Vegte-Bolmer Marga M Graumans Wouter W Siebelink-Stoter Rianne R Kooij Taco W A TWA Marti Matthias M Drakeley Chris C Campo Joseph J JJ van Dam Teunis J P TJP Sauerwein Robert R Bousema Teun T Huynen Martijn A MA
Scientific reports 20180111 1
Plasmodium gametocytes are the sexual forms of the malaria parasite essential for transmission to mosquitoes. To better understand how gametocytes differ from asexual blood-stage parasites, we performed a systematic analysis of available 'omics data for P. falciparum and other Plasmodium species. 18 transcriptomic and proteomic data sets were evaluated for the presence of curated "gold standards" of 41 gametocyte-specific versus 46 non-gametocyte genes and integrated using Bayesian probabilities ...[more]