High-grade cervical intraepithelial neoplasia in human papillomavirus self-sampling of screening non-attenders.

ABSTRACT: BACKGROUND:Self-sampling for human papillomavirus (HPV) offered to women who do not participate in cervical cancer screening is an increasingly popular method to increase screening coverage. The rationale behind self-sampling is that unscreened women harbour a high proportion of undetected precancer lesions. Here, we compare the cervical intraepithelial neoplasia grade 2 or worse (⩾CIN2) detection rate between non-attenders who participated in self-sampling and women attending routine screening. METHODS:A total of 23 632 women who were qualified as non-attenders in the Copenhagen Region were invited for HPV-based self-sampling. Of these, 4824 women returned a self-sample, and HPV-positive women were referred for cytology and HPV co-testing as follow-up. The entire cohort and a reference co

SUBMITTER: Lam JUH 

PROVIDER: S-EPMC5765223 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature