Ontology highlight
ABSTRACT:
SUBMITTER: Li L
PROVIDER: S-EPMC5766044 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Li Lei L Zhu Liren L Ma Cheng C Lin Li L Yao Junjie J Wang Lidai L Maslov Konstantin K Zhang Ruiying R Chen Wanyi W Shi Junhui J Wang Lihong V LV
Nature biomedical engineering 20170510 5
Imaging of small animals has played an indispensable role in preclinical research by providing high dimensional physiological, pathological, and phenotypic insights with clinical relevance. Yet pure optical imaging suffers from either shallow penetration (up to ~1-2 mm) or a poor depth-to-resolution ratio (~1/3), and non-optical techniques for whole-body imaging of small animals lack either spatiotemporal resolution or functional contrast. Here, we demonstrate that standalone single-impulse phot ...[more]