Platelet protein biomarker panel for ovarian cancer diagnosis.
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ABSTRACT:
SUBMITTER: Lomnytska M
PROVIDER: S-EPMC5767003 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
Platelet protein biomarker panel for ovarian cancer diagnosis.
Lomnytska Marta M Pinto Rui R Becker Susanne S Engström Ulla U Gustafsson Sonja S Björklund Christina C Templin Markus M Bergstrand Jan J Xu Lei L Widengren Jerker J Epstein Elisabeth E Franzén Bo B Auer Gert G
Biomarker research 20180112
<h4>Background</h4>Platelets support cancer growth and spread making platelet proteins candidates in the search for biomarkers.<h4>Methods</h4>Two-dimensional (2D) gel electrophoresis, Partial Least Squares Discriminant Analysis (PLS-DA), Western blot, DigiWest.<h4>Results</h4>PLS-DA of platelet protein expression in 2D gels suggested differences between the International Federation of Gynaecology and Obstetrics (FIGO) stages III-IV of ovarian cancer, compared to benign adnexal lesions with a se ...[more]
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