Ontology highlight
ABSTRACT:
SUBMITTER: Yu T
PROVIDER: S-EPMC5767127 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Yu TaChung T Guo Fangfang F Yu Yanan Y Sun Tiantian T Ma Dan D Han Jixuan J Qian Yun Y Kryczek Ilona I Sun Danfeng D Nagarsheth Nisha N Chen Yingxuan Y Chen Haoyan H Hong Jie J Zou Weiping W Fang Jing-Yuan JY
Cell 20170701 3
Gut microbiota are linked to chronic inflammation and carcinogenesis. Chemotherapy failure is the major cause of recurrence and poor prognosis in colorectal cancer patients. Here, we investigated the contribution of gut microbiota to chemoresistance in patients with colorectal cancer. We found that Fusobacterium (F.) nucleatum was abundant in colorectal cancer tissues in patients with recurrence post chemotherapy, and was associated with patient clinicopathological characterisitcs. Furthermore, ...[more]