Ontology highlight
ABSTRACT:
SUBMITTER: Bennstein SB
PROVIDER: S-EPMC5767218 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Frontiers in immunology 20180109
Natural killer T-cells are a subset of innate-like T-cells with the ability to bridge innate and adaptive immunity. There is great interest in harnessing these cells to improve tumor therapy; however, greater understanding of invariant NKT (iNKT) cell biology is needed. The first step is to learn more about NKT development within the thymus. Recent studies suggest lineage separation of murine iNKT cells into iNKT1, iNKT2, and iNKT17 cells instead of shared developmental stages. This review will ...[more]