Decay of HIV DNA in the Reservoir and the Impact of Short Treatment Interruption in Kenyan Infants.
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ABSTRACT:
SUBMITTER: Pankau MD
PROVIDER: S-EPMC5767951 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
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Decay of HIV DNA in the Reservoir and the Impact of Short Treatment Interruption in Kenyan Infants.
Pankau Mark D MD Wamalwa Dalton D Benki-Nugent Sarah S Tapia Kenneth K Ngugi Evelyn E Langat Agnes A Otieno Vincent V Moraa Helen H Maleche-Obimbo Elizabeth E Overbaugh Julie J John-Stewart Grace C GC Lehman Dara A DA
Open forum infectious diseases 20171209 1
We compared change in HIV reservoir DNA following continued antiretroviral therapy (ART) vs short treatment interruption (TI) in early ART-treated Kenyan infants. While HIV DNA in the reservoir decayed with continued ART, HIV DNA levels were similar to pre-TI HIV DNA reservoir levels in most children after short TI. ...[more]
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