Ontology highlight
ABSTRACT:
SUBMITTER: Yang Z
PROVIDER: S-EPMC5768346 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Yang Zhao Z He Jin J Gao Peng P Niu Yi Y Zhang Jie J Wang Lei L Liu Meiyue M Wei Xiaomei X Liu Chunling C Zhang Chao C Wang Wei W Du Jiayi J Li Hongmin H Hu Wanning W Sun Guogui G
Oncotarget 20171208 69
MicroRNAs (miRNAs) are key regulators of multiple cancers, including non-small cell lung carcinoma (NSCLC). The aim of this study was to determine the expression pattern of miR-769-5p in NSCLC and to investigate its biological role during tumorigenesis. We showed that miR-769-5p was significantly downregulated and predicted poor prognosis in NSCLC compared with corresponding normal tissues. We then investigated its function and found that miR-769-5p significantly inhibited cell proliferation, mi ...[more]