Ontology highlight
ABSTRACT:
SUBMITTER: Jocken JWE
PROVIDER: S-EPMC5768634 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Jocken Johan W E JWE González Hernández Manuel A MA Hoebers Nicole T H NTH van der Beek Christina M CM Essers Yvonne P G YPG Blaak Ellen E EE Canfora Emanuel E EE
Frontiers in endocrinology 20180111
<h4>Background and aims</h4>Gut-derived short-chain fatty acids (SCFA), formed by microbial fermentation of dietary fibers, are believed to be involved in the etiology of obesity and diabetes. Previous data from our group showed that colonic infusions of physiologically relevant SCFA mixtures attenuated whole-body lipolysis in overweight men. To further study potential mechanisms involved in the antilipolytic properties of SCFA, we aimed to investigate the <i>in vitro</i> effects of SCFA incubat ...[more]