Evaluation of the effects of space allowance on measures of animal welfare in laboratory mice.
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ABSTRACT:
SUBMITTER: Bailoo JD
PROVIDER: S-EPMC5768730 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
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Evaluation of the effects of space allowance on measures of animal welfare in laboratory mice.
Bailoo Jeremy D JD Murphy Eimear E Varholick Justin A JA Novak Janja J Palme Rupert R Würbel Hanno H
Scientific reports 20180115 1
We studied how space allowance affects measures of animal welfare in mice by systematically varying group size and cage type across three levels each in both males and females of two strains of mice (C57BL/6ByJ and BALB/cByJ; n = 216 cages, a total of 1152 mice). This allowed us to disentangle the effects of total floor area, group size, stocking density, and individual space allocation on a broad range of measures of welfare, including growth (food and water intake, body mass); stress physiolog ...[more]
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