Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice.
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ABSTRACT:
SUBMITTER: Pont I
PROVIDER: S-EPMC5770017 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice.
Pont Isabel I Calatayud-Pascual Aracely A López-Castellano Alicia A Albelda Elena P EP García-España Enrique E Martí-Bonmatí Luis L Frias Juan C JC Albelda M Teresa MT
PloS one 20180116 1
Fumagillin-loaded liposomes were injected into ApoE-KO mice. The animals were divided into several groups to test the efficacy of this anti-angiogenic drug for early treatment of atherosclerotic lesions. Statistical analysis of the lesions revealed a decrease in the lesion size after 5 weeks of treatment. ...[more]
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