Ontology highlight
ABSTRACT:
SUBMITTER: Rahman MM
PROVIDER: S-EPMC5770437 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Rahman Mohammad Mubinur MM Andberg Martina M Koivula Anu A Rouvinen Juha J Hakulinen Nina N
Scientific reports 20180116 1
The Ilv/ED dehydratase protein family includes dihydroxy acid-, gluconate-, 6-phosphogluconate- and pentonate dehydratases. The members of this family are involved in various biosynthetic and carbohydrate metabolic pathways. Here, we describe the first crystal structure of D-xylonate dehydratase from Caulobacter crescentus (CcXyDHT) at 2.7 Å resolution and compare it with other available enzyme structures from the IlvD/EDD protein family. The quaternary structure of CcXyDHT is a tetramer, and ea ...[more]