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Detection of mcr-4 positive Salmonella enterica serovar Typhimurium in clinical isolates of human origin, Italy, October to November 2016.


ABSTRACT: In this study we report the detection of the recently described mcr-4 gene in two human isolates of Salmonella enterica serovar Typhimurium. The strains were isolated from faecal samples of two Italian patients with gastroenteritis, collected in 2016. The identified mcr-4 genes (variant mcr-4.2) differed from the mcr-4 gene originally described in a Salmonella strain of swine origin from Italy. Salmonella species could represent a hidden reservoir for mcr genes.

SUBMITTER: Carretto E 

PROVIDER: S-EPMC5770850 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature

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Detection of <i>mcr-4</i> positive S<i>almonella enterica</i> serovar Typhimurium in clinical isolates of human origin, Italy, October to November 2016.

Carretto Edoardo E   Brovarone Flavia F   Nardini Paola P   Russello Giuseppe G   Barbarini Daniela D   Pongolini Stefano S   Gagliotti Carlo C   Carattoli Alessandra A   Sarti Mario M  

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20180101 2


In this study we report the detection of the recently described <i>mcr-4</i> gene in two human isolates of <i>Salmonella enterica</i> serovar Typhimurium. The strains were isolated from faecal samples of two Italian patients with gastroenteritis, collected in 2016. The identified <i>mcr-4</i> genes (variant <i>mcr-4.2</i>) differed from the <i>mcr-4</i> gene originally described in a <i>Salmonella</i> strain of swine origin from Italy. <i>Salmonella</i> species could represent a hidden reservoir  ...[more]

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