Ontology highlight
ABSTRACT:
SUBMITTER: Kilgore AM
PROVIDER: S-EPMC5771264 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Kilgore Augustus M AM Welsh Seth S Cheney Elizabeth E EE Chitrakar Alisha A Blain Trevor J TJ Kedl Benjamin J BJ Hunter Chris A CA Pennock Nathan D ND Kedl Ross M RM
ImmunoHorizons 20180101 1
It is well accepted that the innate response is a necessary prerequisite to the formation of the adaptive response. This is true for T cell responses against infections or adjuvanted subunit vaccination. However, specific innate parameters with predictive value for the magnitude of an adjuvant-elicited T cell response have yet to be identified. We previously reported how T cell responses induced by subunit vaccination were dependent on the cytokine IL-27. These findings were unexpected, given th ...[more]