Unknown

Dataset Information

0

Determinants of Long-Term Neurological Recovery Patterns Relative to Hospital Discharge Among Cardiac Arrest Survivors.


ABSTRACT: OBJECTIVE:To explore factors associated with neurological recovery at 1 year relative to hospital discharge after cardiac arrest. DESIGN:Observational, retrospective review of a prospectively collected cohort. SETTING:Medical or surgical ICUs in a single tertiary care center. PATIENTS:Older than 18 years, resuscitated following either in-hospital or out-of-hospital cardiac arrest and considered for targeted temperature management between 2007 and 2013. INTERVENTIONS:None. MEASUREMENTS AND MAIN RESULTS:Logistic regressions to determine factors associated with a poor recovery pattern after 1 year, defined as persistent Cerebral Performance Category Score 3-4 or any worsening of Cerebral Performance Category Score relative to discharge status. In total, 30% (117/385) of patients survived to hospital discharge; among those discharged with Cerebral Performance Category Score 1, 2, 3, and 4, good recovery pattern was seen in 54.5%, 48.4%, 39.5%, and 0%, respectively. Significant variables showing trends in associations with a poor recovery pattern (62.5%) in a multivariate model were age more than 70 years (odds ratio, 4; 95% CIs, 1.1-15; p = 0.04), Hispanic ethnicity (odds ratio, 4; CI, 1.2-13; p = 0.02), and discharge disposition (home needing out-patient services (odds ratio, 1), home requiring no additional services (odds ratio, 0.15; CI, 0.03-0.8; p = 0.02), acute rehabilitation (odds ratio, 0.23; CI, 0.06-0.9; p = 0.04). CONCLUSIONS:Patients discharged with mild or moderate cerebral dysfunction sustained their risk of neurological worsening within 1 year of cardiac arrest. Old age, Hispanic ethnicity, and discharge disposition of home with out-patient services may be associated with a poor 1 year neurological recovery pattern after hospital discharge from cardiac arrest.

SUBMITTER: Agarwal S 

PROVIDER: S-EPMC5771814 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature

altmetric image

Publications

Determinants of Long-Term Neurological Recovery Patterns Relative to Hospital Discharge Among Cardiac Arrest Survivors.

Agarwal Sachin S   Presciutti Alex A   Roth William W   Matthews Elizabeth E   Rodriguez Ashley A   Roh David J DJ   Park Soojin S   Claassen Jan J   Lazar Ronald M RM  

Critical care medicine 20180201 2


<h4>Objective</h4>To explore factors associated with neurological recovery at 1 year relative to hospital discharge after cardiac arrest.<h4>Design</h4>Observational, retrospective review of a prospectively collected cohort.<h4>Setting</h4>Medical or surgical ICUs in a single tertiary care center.<h4>Patients</h4>Older than 18 years, resuscitated following either in-hospital or out-of-hospital cardiac arrest and considered for targeted temperature management between 2007 and 2013.<h4>Interventio  ...[more]

Similar Datasets

| S-EPMC9157268 | biostudies-literature
| S-EPMC6632185 | biostudies-literature
| S-EPMC10404449 | biostudies-literature
| S-EPMC6506695 | biostudies-literature
| S-EPMC4404214 | biostudies-literature
| S-EPMC5747564 | biostudies-literature
| S-EPMC8088455 | biostudies-literature
| S-EPMC3652256 | biostudies-literature
| S-EPMC7527362 | biostudies-literature
| S-EPMC8940794 | biostudies-literature