Ontology highlight
ABSTRACT:
SUBMITTER: Hryciuk B
PROVIDER: S-EPMC5774463 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Hryciuk Beata B Szymanowski Bartosz B Romanowska Anna A Salt Ewa E Wasąg Bartosz B Grala Bartłomiej B Jassem Jacek J Duchnowska Renata R
Oncology letters 20171122 2
Gemcitabine (GCB) is a pyrimidine antimetabolite widely used in various solid tumors as a single agent or as a component of multidrug regimens. In the majority of patients, GCB is well tolerated, however life-threatening complications occasionally occur. The current report presents four cases of severe acute toxicity, which included two that were fatal, following administration of GCB alone or in combination with cisplatin. Of the four cases, in one, a Naranjo Adverse Drug Reaction Probability S ...[more]