Simultaneous MR thermometry and acoustic radiation force imaging using interleaved acquisition.

ABSTRACT: PURPOSE:A novel and practical method for simultaneously performing MR acoustic radiation force imaging (ARFI) and proton resonance frequency (PRF)-shift thermometry has been developed and tested. This could be an important tool for evaluating the success of MR-guided focused ultrasound procedures for which MR-thermometry measures temperature and thermal dose and MR-ARFI detects changes in tissue mechanical properties. METHODS:MR imaging was performed using a gradient recalled echo segmented echo-planar imaging pulse sequence with bipolar motion encoding gradients (MEG). Images with ultrasound pulses (ON) and without ultrasound pulses (OFF) during the MEG were interleaved at the repetition time (TR) level. ARFI displacements were calculated by complex subtraction of ON-OFF images, and PRF temperature maps were calculated by baseline subtraction. Evaluations in tissue-mimicking phantoms and ex vivo porcine brain tissue were performed. Constrained reconstruction improved the temporal resolution of dynamic measurements. RESULTS:Simultaneous maps of displacement and temperature were acquired in 2D and 3D while keeping tissue heating?

SUBMITTER: de Bever JT 

PROVIDER: S-EPMC5775920 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature