Ontology highlight
ABSTRACT:
SUBMITTER: Mills DM
PROVIDER: S-EPMC5777621 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Mills Dawn M DM Calvo-Marzal Percy P Pinzon Jeffer M JM Armas Stephanie S Kolpashchikov Dmitry M DM Chumbimuni-Torres Karin Y KY
Electroanalysis 20161115 3
Electrochemical hybridization sensors have been explored extensively for analysis of specific nucleic acids. However, commercialization of the platform is hindered by the need for attachment of separate oligonucleotide probes complementary to a RNA or DNA target to an electrode's surface. Here we demonstrate that a single probe can be used to analyze several nucleic acid targets with high selectivity and low cost. The universal electrochemical four-way junction (4J)-forming (UE4J) sensor consist ...[more]