Lethal Respiratory Disease Associated with Human Rhinovirus C in Wild Chimpanzees, Uganda, 2013.
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ABSTRACT:
SUBMITTER: Scully EJ
PROVIDER: S-EPMC5782908 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
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Lethal Respiratory Disease Associated with Human Rhinovirus C in Wild Chimpanzees, Uganda, 2013.
Scully Erik J EJ Basnet Sarmi S Wrangham Richard W RW Muller Martin N MN Otali Emily E Hyeroba David D Grindle Kristine A KA Pappas Tressa E TE Thompson Melissa Emery ME Machanda Zarin Z Watters Kelly E KE Palmenberg Ann C AC Gern James E JE Goldberg Tony L TL
Emerging infectious diseases 20180201 2
We describe a lethal respiratory outbreak among wild chimpanzees in Uganda in 2013 for which molecular and epidemiologic analyses implicate human rhinovirus C as the cause. Postmortem samples from an infant chimpanzee yielded near-complete genome sequences throughout the respiratory tract; other pathogens were absent. Epidemiologic modeling estimated the basic reproductive number (R<sub>0</sub>) for the epidemic as 1.83, consistent with the common cold in humans. Genotyping of 41 chimpanzees and ...[more]
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