Ontology highlight
ABSTRACT:
SUBMITTER: Ho WC
PROVIDER: S-EPMC5783951 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Ho Wei-Chin WC Zhang Jianzhi J
Nature communications 20180124 1
Organismal adaptation to a new environment may start with plastic phenotypic changes followed by genetic changes, but whether the plastic changes are stepping stones to genetic adaptation is debated. Here we address this question by investigating gene expression and metabolic flux changes in the two-phase adaptation process using transcriptomic data from multiple experimental evolution studies and computational metabolic network analysis, respectively. We discover that genetic changes more frequ ...[more]