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The impact of pre and perinatal lifestyle factors on child long term health and social outcomes: a systematic review.


ABSTRACT: To understand the full extent of the impact of a trial, it is important to consider the long-term consequences of outcomes beyond the trial follow-up period, especially for early year's interventions. A systematic review of the literature associated with the long-term consequences of four key outcomes from the Building Blocks trial, specifically, low birth weight, smoking during pregnancy, interval to subsequent pregnancy and A&E attendance or inpatient admission was conducted. These factors were guided by the funders, the Department of Health, as being of particular interest in the UK context. Relevant studies were identified from a number of sources including large databases, reference checking and citation searching. The search yielded 3665 papers, 43 of which were considered appropriate for inclusion. Of these, 29 were relating to smoking during pregnancy, 13 to low birth weight, 0 to A&E attendances during early childhood and 1 to short (

SUBMITTER: Bell K 

PROVIDER: S-EPMC5783983 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature

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The impact of pre and perinatal lifestyle factors on child long term health and social outcomes: a systematic review.

Bell Kerry K   Corbacho Belen B   Ronaldson Sarah S   Richardson Gerry G   Torgerson David D   Robling Michael M  

Health economics review 20180124 1


To understand the full extent of the impact of a trial, it is important to consider the long-term consequences of outcomes beyond the trial follow-up period, especially for early year's interventions. A systematic review of the literature associated with the long-term consequences of four key outcomes from the Building Blocks trial, specifically, low birth weight, smoking during pregnancy, interval to subsequent pregnancy and A&E attendance or inpatient admission was conducted. These factors wer  ...[more]

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