Ontology highlight
ABSTRACT:
SUBMITTER: Avci ME
PROVIDER: S-EPMC5785479 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Avci M Ender ME Keskus Ayse Gokce AG Targen Seniye S Isilak M Efe ME Ozturk Mehmet M Atalay Rengul Cetin RC Adams Michelle M MM Konu Ozlen O
Scientific reports 20180125 1
Acetylcholinesterase (AChE), an enzyme responsible for degradation of acetylcholine, has been identified as a prognostic marker in liver cancer. Although in vivo Ache tumorigenicity assays in mouse are present, no established liver cancer xenograft model in zebrafish using an ache mutant background exists. Herein, we developed an embryonic zebrafish xenograft model using epithelial (Hep3B) and mesenchymal (SKHep1) liver cancer cell lines in wild-type and ache <sup>sb55</sup> sibling mutant larva ...[more]