Ontology highlight
ABSTRACT:
SUBMITTER: Johnston JR
PROVIDER: S-EPMC5787451 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Oncotarget 20171204 1
Troponin is a heterotrimeric Ca<sup>2+</sup>-binding protein that has a well-established role in regulating striated muscle contraction. However, mounting evidence points to novel cellular functions of troponin, with profound implications in cancer, cardiomyopathy pathogenesis and skeletal muscle aging. Here, we highlight the non-canonical roles and aberrant expression patterns of troponin beyond the sarcomeric milieu. Utilizing bioinformatics tools and online databases, we also provide pathway, ...[more]