ACTN3, Morbidity, and Healthy Aging.
Ontology highlight
ABSTRACT:
SUBMITTER: Pickering C
PROVIDER: S-EPMC5787547 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
<i>ACTN3</i>, Morbidity, and Healthy Aging.
Pickering Craig C Kiely John J
Frontiers in genetics 20180124
As human longevity increases, recent research has focused on the maintenance of optimal health during old age. One such area of focus is that of muscle function in the elderly, with a loss of muscle mass increasing the risk of negative outcomes such as sarcopenia and a decrease in bone mineral density. In this mini-review, we focus on the impact of a single nucleotide polymorphism in <i>ACTN3</i>, shown to impact muscle phenotype in elite athletes, on loss of muscle function, maintenance of bone ...[more]
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