A Two-Stage Whole-Genome Gene Expression Association Study of Young-Onset Hypertension in Han Chinese Population of Taiwan.
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ABSTRACT:
SUBMITTER: Chiang KM
PROVIDER: S-EPMC5789005 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
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A Two-Stage Whole-Genome Gene Expression Association Study of Young-Onset Hypertension in Han Chinese Population of Taiwan.
Chiang Kuang-Mao KM Yang Hsin-Chou HC Pan Wen-Harn WH
Scientific reports 20180129 1
Hypertension is an important public health problem in the world. Since the intermediate position of the gene expression between genotype and phenotype makes it suitable to link genotype to phenotype, we carried out a two-stage whole-genome gene expression association study to find differentially expressed genes and pathways for hypertension. In the first stage, 126 cases and 149 controls were used to find out the differentially expressed genes. In the second stage, an independent set of samples ...[more]
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