Ontology highlight
ABSTRACT:
SUBMITTER: Focosi D
PROVIDER: S-EPMC5789275 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Focosi Daniele D Amabile Giovanni G
Cells 20171227 1
Red blood cells and platelets are anucleate blood components indispensable for oxygen delivery and hemostasis, respectively. Derivation of these blood elements from induced pluripotent stem (iPS) cells has the potential to develop blood donor-independent and genetic manipulation-prone products to complement or replace current transfusion banking, also minimizing the risk of alloimmunization. While the production of erythrocytes from iPS cells has challenges to overcome, such as differentiation i ...[more]