Current Advances in Aptamers for Cancer Diagnosis and Therapy.
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ABSTRACT:
SUBMITTER: Hori SI
PROVIDER: S-EPMC5789359 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Publications
Current Advances in Aptamers for Cancer Diagnosis and Therapy.
Hori Shin-Ichiro SI Herrera Alberto A Rossi John J JJ Zhou Jiehua J
Cancers 20180103 1
Nucleic acid aptamers are single-stranded oligonucleotides that interact with target molecules with high affinity and specificity in unique three-dimensional structures. Aptamers are generally isolated by a simple selection process called systematic evolution of ligands by exponential enrichment (SELEX) and then can be chemically synthesized and modified. Because of their high affinity and specificity, aptamers are promising agents for biomarker discovery, as well as cancer diagnosis and therapy ...[more]
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