Ontology highlight
ABSTRACT:
SUBMITTER: Bandini C
PROVIDER: S-EPMC5789371 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Bandini Cecilia C Pupuleku Aldi A Spaccarotella Elisa E Pellegrino Elisa E Wang Rui R Vitale Nicoletta N Duval Carlotta C Cantarella Daniela D Rinaldi Andrea A Provero Paolo P Di Cunto Ferdinando F Medico Enzo E Bertoni Francesco F Inghirami Giorgio G Piva Roberto R
Cancers 20180118 1
Systemic anaplastic large cell lymphomas (ALCL) are a category of T-cell non-Hodgkin's lymphomas which can be divided into anaplastic lymphoma kinase (ALK) positive and ALK negative subgroups, based on ALK gene rearrangements. Among several pathways aberrantly activated in ALCL, the constitutive activation of signal transducer and activator of transcription 3 (STAT3) is shared by all ALK positive ALCL and has been detected in a subgroup of ALK negative ALCL. To discover essential mediators of ST ...[more]